MACS (Model-based Analysis of ChIP-Seq) is an analysis tool for NGS ChIP-Seq data. MACS empirically models the length of the sequenced ChIP fragments and uses it to improve the spatial resolution of predicted binding sites.
MACS also uses a dynamic Poisson distribution to effectively capture local biases in the genome sequence, allowing for more sensitive and robust prediction. MACS compares can be used for ChIP-Seq with or without control samples.
Free to use and open source under BSD 3-Clause License.
Version on CSC's Servers
- Puhti: 22.214.171.124, 3.0.0a7
- Chipster graphical user interface
To set up MACS2 and MACS3 commands in puhti, give command:
module load macs
Module macs/126.96.36.199 also loads MACS 3.0.0a7.
After that you can start MACS with command:
macs2 -h macs3 -h