MACS (Model-based Analysis of ChIP-Seq) is an analysis tool for NGS ChIP-Seq data. MACS empirically models the length of the sequenced ChIP fragments and uses it to improve the spatial resolution of predicted binding sites.
MACS also uses a dynamic Poisson distribution to effectively capture local biases in the genome sequence, allowing for more sensitive and robust prediction. MACS compares can be used for ChIP-Seq with or without control samples.
Free to use and open source under BSD 3-Clause License.
Version on CSC's Servers
Puhti: 2.2.6 Chipster graphical user interface
To set up MACS2 commands in puhti, give command:
module load bioconda
After that you can start MACS2 with command:
Larger MACS jobs should be executed as a batch job in Puhti. Puhti User Guide for more information on running batch jobs.